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  • Breast Cancer3m 2s

    ESR1 Mutation as an emerging clinical biomarker metastatic hormone receptor positive Breast Cancer

    Combination of CDK4/6 inhibitors & aromatase inhibitor is recommended for frontline treatment of Hormone receptor positive (ER+ve) Metastatic Breast Cancer. Patients eventually develop disease progression which might be attributed to ESR1 mutations.
    biomarkers esr1 mutation fulvestrant hormone receptor positive mbc serd
  • OncoSpecials50m 57s

    Understanding Biosimilars -An Expert Perspective

    Biosimilars are biologic medicines that are highly similar to an FDA-approved reference product, with no clinically meaningful differences in terms of safety, purity, and potency.
    biosimilar biologics expert perspective
  • Breast Cancer14m 46s

    ESMO 2022 Breast Cancer Comprehensive Coverage

    View comprehensive coverage of Breast Cancer from ESMO 2022
    dose dense adjuvant chemotherapy esmo keynote -522 monarch -3 study
  • Multiple Myeloma11m 40s

    How I Treat Relapsed Refractory Multiple Myeloma

    Treating relapsed or refractory multiple myeloma (RRMM) can be complex and typically involves a combination of therapies based on the patient's previous treatments, overall health, and specific disease characteristics.
    relapsed refractory multiple myeloma treatment combination treatment
  • Multiple Myeloma9m 20s

    Integrating Pomalidomide Based Regimens in Multiple Myeloma

    Integrating pomalidomide and dexamethasone in the treatment of relapsed or refractory multiple myeloma (RRMM) involves using them as a core regimen, often combined with other agents like bortezomib or monoclonal antibodies for enhanced efficacy.
    pomalidomide-dexamethasone rrmm management progression-free survival combination therapies
  • Myelodysplastic Syndromes8m 45s

    Current Challenges in MDS Diagnosis and Consequences

    Bone marrow examination-based diagnosis of MDS with either biopsy or aspirate remains standard of care but is associated with pain, bleeding, difficulty to use the same in elderly patients and hIgh interobserver variability.
    non invasive mds diagnosis web based mds diagnosis tools
  • Breast Cancer8m 46s

    Expert Perspective - How I Treat Metastatic Her2 Positive Breast Cancer

    Anti-HER2 directed therapy remains the cornerstone of care for individuals with HER2-positive metastatic breast cancer (MBC).
    anti-her2 directed therapy her2-positive metastatic breast cancer expert perspective algorithm for management of her2 positive mbc
  • Prostate Cancer49m 18s

    Dissecting the biology of advanced prostate cancer

    Advanced prostate cancer is characterized by intricate biological changes, including genetic and epigenetic alterations, as well as shifts in cellular metabolism.
    advanced prostate cancer cellular metabolism castration-resistant prostate cancer targeted therapies improved patient care
  • Pharmacy37m 20s

    Quality management systems in pharmacy practice

    Dr Scott Soefje, PharmD, Mayo Clinic
    Provides a perspective “Quality Management Systems in Pharmacy Practice”.
    mednrich
  • Breast Cancer11m 28s

    ESR1 Mutation in Hormone Receptor Positive Advanced Breast Cancer

    ESR1 mutation leads to ligand independent activation of estrogen receptor. ESR1 mutations were first described in 1997 & their role remain underestimated as initial research was focused on primary tumor wherein these mutations were absent.
    aromatase inhibitor resistance hr +ve mbc esr1 mutation fulvestrant

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